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Short CommunicationOpen Access

Esophageal Choke and its Management in a Thorough Bred Horse

Adolfo F Godoy Pinto*

DOI: 10.26717/BJSTR.2017.01.000194

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    • Department of Clinical Sciences, University Of Chile, South Africa

    *Corresponding author: Adolfo F Godoy Pinto, Department Of Clinical Sciences, Area Of Internal Medicine And Equine Surgery, Faculty Of Veterinary Sciences, University Of Chile, South Africa

Received: July 10, 2017;   Published: July 14, 2017

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Abstract

Microbubbles system is a newly invented non-invasive technique in which, in the presence of ultrasound waves or harmonic sounds micropores shrinks and agitated to produce micro bubbles within the applied area. These bubbles have the capability to target any perfused tissues within our body. Recently it was postulated that due to its narrow size range (1 to 10μm vesicular diameter) it can get easily engulf by phagocytic blood cells which can be very effective on lymphocytic cancer. Micro bubbles are prepared by using mechanical agitation, ultrasonication, pressurized gas-liquid mixing system etc. Micro bubbles are made up of a monolayer of protein shells, lipid shells, surfactant shells, polymer shells, Polyelectrolyte multilayer shells. Initially, microbubbles are used as diagnostic tools but due to its versatility of uses and properties of surface conjugation of proteins, genes, micro molecular nutrients, drugs slowly it’s becoming a therapeutic delivery tool. ALBUNEX® (GE Healthcare) was the first albumin conjugated micro bubble which was been approved by US-FDA. Recently importance is been given for brain targeting using Micro bubble carrier system. It was observed that using passive and active transport micro streamed bubbles can able to transport through Blood Brain Barrier (BBB). It is very important to give more importance to its stability and canonization of globules for more industrial acceptability.

Introduction| Clinical Case| Treatment| Conclusion| References|