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A New Look At the Origin of the Immune System and New Immune Theory of Aging: Lymphocyte Regulation of Cellular Growth of Somatic Tissues: (History and Modern Concepts)

Volume 1 - Issue 6

Vitaly I Dontsov*1,2

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    • 1Russian Academy of Sciences, Moscow, Russia,
    • 2Sechenov First Moscow State Medical University, Russia

    *Corresponding author: Vitaly I Dontsov, Institute for Systems Analysis, Federal Research Center “Computer Science and Control”, Russian Academy of Sciences, 117312 Moscow, Russia

Received: November 14, 2017;   Published: November 28, 2017

DOI: 10.26717/BJSTR.2017.01.000544

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Abstract

Specialized cell populations should exist to carry out intercellular regulation of the growth of various types somatic tissues (“cellular hyper cycle”). Based on the data of immunology and cell biology, it is suggested that such a system should be represented by specialized T-lymphoid cells. The function of the regulation of growth of various types of somatic tissues may be more primary in phylogenies in the formation of the immune system (new theory of the origin of the immune system). The age-related immune decrease in the function of such regulatory cells may be the main mechanism of aging of the organism’s self-renewing somatic tissues and may determine an age-related decrease in the growth potential of tissues of an aged organism (new immune theory of aging).

Key words: Cell Growth Regulation; Immunity; Theory of Immunity; Aging; Theory of Aging

Abstract| Introduction| T-Lymphocytes as Regulators of Somatic Cell Growth| New theory of the Origin of the Immune system| A new immune-Regulatory theory of Aging| Conclusion| References|