Case ReportOpen Access

Cytohistopathological Diagnosis of Solitary Plasmacytoma of Clavicle: A Rare Site for a Rare Tumor

Volume 2 - Issue 1

**Nirmalesh Mahata¹, Indranil Chakrabarti^2*, Palash Kumar Mandal³ and Bidyut K Goswami²**

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- ¹MAL superspeciality Hospital, India
- ²Department of Pathology, North Bengal Medical College, India
- ³Department of Pathology, College Of Medicine and Sagore Dutta Hospital, India
*Corresponding author: Dr. Indranil Chakrabarti, Associate Professor, Department of Pathology, North Bengal Medical College, Sushrutanagar, Darjeeling, West Bengal, India 734012

Received: January 08, 2018; Published: January 16, 2018

DOI: 10.26717/BJSTR.2018.02.000660

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Abstract

Plasmacytoma refers to a malignant tumor composed of abnormal plasma cells which grows within soft tissue or within the axial skeleton. There are three distinct groups of plasmacytoma, of which the solitary plasmacytoma of bone (SPB), accounts for 3-5% of all plasma cell malignancies. The World Health Organization define solitary plasmacytoma of bone (SPB) as a localized bone tumor consisting of plasma cell identical to those seen in plasma cell myeloma, which appears as a solitary lytic lesion on radiological examination. Here, we report a case of a 50-year old male who presented with swelling of the medial end of clavicle of right side and inability to raise his right hand for the last 3 months. Fine needle aspiration cytology revealed cellular smears composed of sheets of plasma cells with bi-nucleate and multi-nucleated forms. The swelling was operated and subsequent histopathology revealed a solitary plasmacytoma of right clavicle.

The absence of any other osteopenic lesion on radiograph, negative bone scan, absence of marrow involvement by plasma cell or any evidence of anemia, hypercalcemia, hyperuricemia, nephropathy, respiratory and urinary tract infection indicated that there was no systemic myeloma. The patient was treated with surgery and radiotherapy. On subsequent follow up at 15 month, the patient developed multiple myeloma. Thus, here we report a very rare case of solitary plasmacytoma of clavicle diagnosed by cytology and later confirmed by histopathology.

Keywords: Solitary Plasmacytoma; FNAC; Multiple Myeloma

Abbreviations: SPB: Solitary Plasmacytoma of Bone; EMP: Extramedullary Plasmacytoma