Mini ReviewOpen Access

Some Nano Bio-Mofs Evaluated For Storage Purpose of Drugs

Volume 2 - Issue 1

Tabinda Sattar and Muhammad Athar*

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- Assistant professor, Institute of Chemical Sciences, Pakistan
*Corresponding author: Muhammad Athar, assistant professor, institute of chemical sciences, Bahaudin zakariya university Multan, Pakistan

Received: January 08, 2018; Published: January 25, 2018

DOI: 10.26717/BJSTR.2018.02.000693

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Abstract

Nano bio-MOF compounds 3-5 (copper serinate, copper prolinate and copper threoninate) have been evaluated for successful in vitro drugs adsorption of three drugs, named terazosine, telmisartan and glimpiride. Pore sizes and BET surface areas were recorded on N2 adsorption isotherms. In order to elaborate the phenomenon of in vitro drugs adsorption in all these compounds we obtained TGA and PXRD spectra of them. The high performance liquid chromatography (HPLC) was used to monitor the amounts of adsorbed drugs and its slow release from all these compounds.

Keywords: Nano bio-MOFs; Invitro; Drugs adsorption; TGA; PXRD; HPLC

Abbreviations: MOFs: Metal Organic Frameworks; SEM: Scanning Electron Microscopic; HPLC: High Performance Liquid Chromatography; TGA: Thermo Gravimetric Analysis

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