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Research ArticleOpen Access

Explaining the Risk Factors Increase in Cardiovascular Disease Mortality in Chinese Patients

Volume 5 - Issue 3

Jie Zhang*1,2, Hongwei Yan1, Longbin Ren1,2, Jingjing Chen1,2, Zhe Mu3, Li Peng3, Lijuan Zhang1,2 and Jue Li1,2

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    • 1Shanghai East Hospital, Tongji University School of Medicine, China
    • 2Institute of Clinical Epidemiology and Evidence - based medicine, Tongji University School of Medicine, China
    • 3Shanghai Key Laboratory of Meteorology and Health, China

    *Corresponding author: : Jie Zhang, Shanghai East Hospital, Key Laboratory of Arrhythmias, Ministry of Education, Tongji University School of Medicine, Shanghai 200120, China

Received: May 28, 2018;   Published: June 11, 2018

DOI: 10.26717/BJSTR.2018.05.001194

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Cardiovascular disease (CVD) mortality is rising in many developing countries. There are many reasons for the mortality. In this study, we applied the IMPACT model to examine how much of the increase in CVD mortality in Beijing and Shanghai, two biggest cities in China. Also, we explored the changes of cardiovascular disease risk factors and assessed the influence of medication treatments on CVD mortality. The patients were enrolled from 2004 to 2010. The result showed that there was an increasing mortality rate of CVD by a negative age gradient in men and women after 45 years old. Most of the prevalence of CVD in different risk factor groups had an increased trend from 2008 to 2010, such as high blood pressure (BP), diabetes mellitus (DM), stoke, peripheral arterial disease (PAD) and coronary heart disease (CHD). From 2004 to 2010, medical treatments in individuals together prevented or postponed almost 205 deaths in 2010. Substantial contributions came from treats of ACEI (26%), CCP (25%), Statins (23%), beta-receptor blocker (17%) and Diuretic (9%). Due to a few numbers of eligible patients who took Fibrates, there was 0% DPPs. The model fit results were good in BP and DM groups.

Keywords: Cardiovascular disease; ACEI; IMPACT model; Mortality

Abstract| Introduction| MMaterials and Methods| Results| Discussion| Acknowledgment| References|