Okadaic Acid Induces the Rats’ Memory
Impairment and Tau Protein Hyperphosphorylation
And Intervened by Flavonoids from Stem and Leaf of
Scutellaria Baicalensis Georgi

Cheng Jianjun; Shang Yazhen

doi:10.26717/BJSTR.2018.09.001842

OpinionOpen Access

Okadaic Acid Induces the Rats’ Memory Impairment and Tau Protein Hyperphosphorylation And Intervened by Flavonoids from Stem and Leaf of Scutellaria Baicalensis Georgi

Volume 9 - Issue 4

Cheng Jianjun and Shang Yazhen*

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- Institute of Traditional Chinese Medicine, Chengde Medical College, China
*Corresponding author: Shang Yazhen, Institute of Traditional Chinese Medicine, Chengde Medical College/Hebei Province Key Research Office of Traditional Chinese Medicine Against Dementia/Hebei Province Key Laboratory of Traditional Chinese Medicine Research and Development, Chengde, Hebei 067000, PR China

Received: October 03, 2018; Published: October 09, 2018

DOI: 10.26717/BJSTR.2018.09.001842

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Abstract

Abbreviations : AD: ALZHEIMER’S DISEASE; NFTs: Neurofibrillary Tangles; P-Tau: Phosphorylated Tau; SP: Senile Plaques; PHF: Paired Helical Filament; CDK5: Cyclin-Dependent Kinase 5; Tyr: phosphorylation at tyrosine; Ser: serine; PKA: protein kinase; GSK3β: Glycogen Synthase Kinase 3β; OA: Okadaic Acid

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