Subcortical White Matter Damage in A Patient
With Early Stage Lupus Nephritis

Sin Yi Lyu; Hsiang Cheng Chen; Chun Chi Lu

doi:10.26717/BJSTR.2018.11.002142

Case ReportOpen Access

Subcortical White Matter Damage in A Patient With Early Stage Lupus Nephritis

Volume 11 - Issue 4

**Sin Yi Lyu¹, Hsiang Cheng Chen² and Chun Chi Lu*²**

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- ¹Department of Radiology, Taiwan
- ²Division of Rheumatology/Immunology and Allergy, Taiwan

Received: November 21, 2018; Published: December 04, 2018

DOI: 10.26717/BJSTR.2018.11.002142

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Abstract

Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) refers to neurological or psychological manifestations, in which headaches and seizures are the most common clinical features. The most common lesions on brain Magnetic Resonance Imaging (MRI) of patients with NPSLE were white matter hyperintense lesions. Numbers and size of lesions were significantly higher in patients with lupus nephritis. This “case report” demonstrates the most common differential diagnoses of brain MRI imaging for patients with simultaneous NPSLE and lupus nephritis, including white matter disease, progressive encephalopathy and posterior reversible encephalopathy syndrome.

Abbreviations : NPSLE: Neuropsychiatric Systemic Lupus Erythematosus; MRI: Magnetic Resonance Imaging; LN: Lupus Nephritis; PRES: Posterior Reversible Encephalopathy Syndrome; DWI: Diffusion-Weighted Imaging; ADC: Apparent Diffusion Coefficient

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