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Essential Quality Analysis Criteria in Forensic Genetics Identification: A Position Statement of Italian Society of Human Genetics

Volume 12 - Issue 2

Giardina Emiliano*1,2, Piluso Giulio3, Del Vecchio Blanco Francesca3, Nutini Anna Lucia4, Ragazzo Michele1, Manzo Laura1, Binni Francesco5, D’Ambrosio Anna5, Di Natale Manuela6, Pietrangeli Ilenia7, Piumelli Nunzia7, Zampatti Stefania2,8, Torrente Isabella9, Mari Francesca10, Bruttini Mirella11,12, Amitrano Sara13, Raso Barbara14, Salvaderi Luca15, Novelli Giuseppe1 and Grammatico Paola5

  • Author Information Open or Close
    • 1Department of Biomedicine and Prevention, School of Medicine, University of Rome “Tor Vergata”, Rome, Italy
    • 2Laboratory of Genomic Medicine, Fondazione Santa Lucia IRCCS, Rome, Italy
    • 3Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, Italy
    • 4Diagnostic Genetics Unit, Azienda Ospedaliero-Universitaria “Careggi”, Florence, Italy
    • 5Medical Genetics, Molecular Medicine Department, Sapienza University of Rome, San Camillo-Forlanini Hospital, Rome, Italy
    • 6Department of Biology, University of Naples Federico II, Naples, Italy
    • 7Central Laboratory of National DNA Database, Department of Penitentiary Administration, Ministry of Justice, Rome, Italy
    • 8IRCCS Neuromed, Località Camerelle, Pozzilli, Italy
    • 9Mendel Laboratory, Casa Sollievo della Sofferenza Hospital, IRCCS, San Giovanni Rotondo (FG), Italy
    • 10Medical Genetics, Department of Medical Biotechnologies, University of Siena, Siena, Italy
    • 11Medical Genetics, University of Siena, Policlinico Le Scotte, Siena, Italy
    • 12Medical Genetics, Azienda University Hospital, Siena, Italy
    • 13Medical Genetics, Azienda Ospedaliera Universitaria Senese, Siena, Italy
    • 14Servizio di Genetica Medica, Clinica Sant’Anna, Rome, Italy
    • 15Genoma Group, Forensic Unit, Milan, Italy
    • *Corresponding author: Emiliano Giardina, University of Rome Tor Vergata, via Montpellier, 100133, Rome

Received: December 05, 2018;   Published: December 14, 2018

DOI: 10.26717/BJSTR.2018.12.002213

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Abstract

The entry into force of DPR n. 87 of 7th April 2016 relating to the DNA Data Bank requires an implementation upgrade of the Forensic Genetics analysis to ensure the quality of results by the control of the pre-analytical and analytical processes. The decree provides the opportunity to define the operational guidance elements, shared by Italian laboratories in the Forensic Genetics field, aimed at ensuring the quality of data and at producing useful genetic profiles: for this reason, the laboratories who want to contribute to the Bank of DNA data need accreditation in accordance with ISO/IEC 17025. This document represents a brief technical document of the Italian Society of Human Genetics in the aim of supporting laboratories seeking accreditation as well as the Italian National Accreditation Body appointed by the State to perform accreditation activity (ACCREDIA).

Keywords :Criteria of Analysis; Forensic Genetics; Accreditation Activity; ISO

Introduction| Glossary| Acknowledgment| References|